Metabolic Check-up :
Longevity & Anti-Aging Blood Test
with Nutritionist
in Zurich & Geneva

The complete lipid profile provides the clinical foundation of cardiovascular risk assessment and gives context to the ApoB result. Triglycerides are particularly informative. Elevated triglycerides are closely linked to insulin resistance and metabolic syndrome, and they are one of the most sensitive dietary markers in the panel. A drop in triglycerides following nutritional intervention is one of the earliest measurable signs that metabolic health is improving.

Together, these two markers reveal the complete picture of glucose metabolism and insulin sensitivity. HbA1c captures average blood sugar over three months. The HOMA index goes further by calculating insulin resistance directly. Insulin resistance is the metabolic root condition that drives abdominal fat accumulation, cognitive decline, chronic inflammation, elevated triglycerides, and accelerated cellular aging — typically for many years before blood sugar levels become abnormal enough to generate any clinical concern.

Chronic cortisol elevation is a powerful and under-appreciated driver of metabolic dysfunction. Sustained high cortisol promotes visceral fat storage specifically around the abdomen, suppresses immune function, elevates blood sugar, and drives systemic inflammation. A single morning cortisol measurement provides a clear snapshot of the adrenal stress response and flags whether chronic stress is actively accelerating your metabolic aging.

Thyroid function governs the speed of virtually every metabolic process in the body. Even subclinical hypothyroidism — which does not yet meet the clinical threshold for a diagnosis — measurably elevates LDL cholesterol, slows metabolic rate, increases cardiovascular risk, and impairs cognitive performance. For a longevity-focused panel, TSH provides the essential metabolic baseline.

The liver regulates cholesterol synthesis, clears metabolic waste, metabolizes hormones, and manages the inflammatory response. GGT in particular has been identified in research as an independent predictor of cardiovascular and metabolic risk beyond its traditional role as a liver function marker.

Iron stores are increasingly studied in the context of cardiovascular and metabolic health. Elevated ferritin is an independent marker of systemic inflammation and a component of metabolic syndrome in a significant proportion of affected individuals. Iron stores that are too high — not just too low — can be clinically relevant in this context.

Vitamin D deficiency is associated with increased cardiovascular risk, insulin resistance, impaired immune function, cognitive decline, and accelerated biological aging. In Switzerland, vitamin D insufficiency is extremely prevalent during autumn and winter months. In the context of a longevity panel, vitamin D is not simply a nutritional marker — it is a metabolic and immunological one.

Standard CRP detects acute inflammation. High-sensitivity CRP detects the low-grade, chronic, systemic inflammation that produces no obvious symptoms but silently damages blood vessels, brain tissue, and metabolic organs over years. Research consistently identifies elevated hsCRP as one of the strongest independent predictors of cardiovascular events and metabolic disease.

Follicle-Stimulating Hormone rises as ovarian function declines, making it the most reliable early marker of the perimenopausal transition. This transition is far more than a reproductive event — it is a metabolic inflection point. The progressive decline in oestrogen that accompanies rising FSH directly increases cardiovascular risk, accelerates bone mineral loss, alters insulin sensitivity, and affects cognitive function and mood. For women under 50, FSH provides critical context for interpreting the entire Metabolic Check-up.