Vitality Check-up : Fatigue & Burnout blood test with nutritionist in Zurich & Geneva

Most standard blood tests only check TSH. But TSH is a pituitary signal, not a cellular one. It tells you whether the thyroid gland is being stimulated, not whether the cells of your body are actually receiving and using active thyroid hormone. Free T3 and Free T4 provide that information. Reverse T3 goes further still. It is an inactive form of thyroid hormone that competes directly with Free T3 at the receptor level, blocking its action even when all other thyroid markers appear normal. Elevated Reverse T3 may be associated with persistent fatigue, cold sensitivity,slow digestion/digestive problems and brain fog. It is not tested in any standard blood panel in Switzerland.

This group of vitamins is involved in virtually every energy-producing pathway in the body. B12, measured here as Holotranscobalamin, the active bioavailable form, is essential for the production of myelin, the protective sheath around nerve cells that enables efficient signal transmission. When B12 is low, the brain does not receive signals efficiently, leading to mental fatigue, difficulty concentrating, and mood instability. B9 and B6 work alongside B12 in the methylation cycle, a critical biochemical process that affects mood, energy, and cognitive function. Deficiencies in these vitamins are relatively common, particularly in populations with limited sun exposure or dietary imbalance.

HbA1c measures your average blood sugar over three months. The HOMA index goes further by calculating insulin resistance directly, using fasting glucose and fasting insulin together. Insulin resistance is a condition where the body's cells stop responding efficiently to insulin, forcing the pancreas to produce more and more to achieve the same effect. The result is chronic energy crashes after meals, difficulty concentrating, brain fog, unexplained weight gain, and persistent fatigue, often years before blood sugar levels become abnormal on a standard test.

Iron deficiency is one of the most common nutritional cause of fatigue, particularly in women of reproductive age. But the key marker is ferritin, the iron storage protein, not iron itself. Iron levels in the blood can appear normal while ferritin, and therefore your body's actual iron reserves, are critically depleted. Blood iron levels only tell us what is circulating right now; Ferritin reveals the bigger picture. As the protein responsible for iron storage, it is the most reliable way to identify if your body’s deep reserves are depleted. Low ferritin alone, even without anaemia, is sufficient to cause profound tiredness, hair loss, difficulty concentrating, and reduced exercise tolerance. Transferrin provides additional information about iron transport and absorption capacity.

The liver is central to hormone metabolism, toxin clearance, and energy regulation. Impaired liver function slows the clearance of cortisol and other stress hormones and may amplify the effects of adrenal dysfunction and contributing directly to fatigue, mood instability, and hormonal imbalance.

Cortisol is a key hormone involved in the regulation of stress response and energy balance, following a natural daily rhythm with peak levels in the morning.
Measuring cortisol at this time provides an indication of the body's stress response. Variations in cortisol levels may be associated with chronic stress, sleep disturbances, or altered energy regulation, but results should always be interpreted in context.